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Revanesse® Important Safety Information
HA the next generation

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If you are a medical aesthetics provider who would like more information about making the Revanesse® portfolio of products available to your patients, or if you have questions about an order, please use the form to contact us.

Unique formulation

The Revanesse brand of dermal fillers was created with a focus on manufacturing decisions that enhance the product and create a unique patient experience. By reverse-engineering older technology, a novel formulation was developed, taking into account all rheological properties. This innovative approach sets it apart from its  predecessors.

Designed for Safety & Longevity​

Revanesse is meticulously optimized at every level, from the molecular scale to the syringe, ensuring safe and predictable outcomes. Notably, since 2017, there have been zero confirmed cases of delayed onset granulomas associated with Revanesse in the United States.

Manufacturing & Rheology: The Difference Lies in the Details

Revanesse utilizes only high-molecular weight HA which has been shown to be anti-inflammatory.1,2 Adding linear HA fine tunes the rheological properties of Revanesse, which also has one of the lowest swell factors of any FDA approved dermal filler3.

1. High and Low Molecular Weight Hyaluronic Acid Differentially Influence Macrophage Activation. ACS Biomater Sci Eng. 2015; 1(7): 481-493.2.
2. Biocompatibility of Microparticles into Soft Tissue Fillers. Semin Cutan Med Surg. 2004; 23(4): 214-217.2. Testing from Prollenium Medical Technologies Inc. Data on file.
3. Woodward J, Ranjit-Reeves R, Katz DF, Bernardini FP, Fagien S. Comparing Water Absorption of Food and Drug Administration-Approved Hyaluronic Acid Fillers. Dermatol Surg. 2021 Sep 1;47(9):1237-1242. Swell ratio is number of times an HA gel can fully absorb water above its original weight (1X) to reach equilibrium (⇋), in a fully aqueous solution. Not to be confused with edema, which is the swelling of the tissue.

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